{"symbol":"KCNJ5","synonyms":["LQT13","KIR3.4","GIRK4","KATP1"],"name":"potassium channel, inwardly rectifying subfamily J, member 5","description":"This gene encodes an integral membrane protein which belongs to one of seven subfamilies of inward-rectifier potassium channel proteins called potassium channel subfamily J. The encoded protein is a subunit of the potassium channel which is homotetrameric. It is controlled by G-proteins and has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Naturally occurring mutations in this gene are associated with aldosterone-producing adenomas. [provided by RefSeq, Aug 2017]","ncbiEntrezGeneId":3762,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/3762","proteins":[{"symbol":"KCNJ5_HUMAN","href":"/api/1.0/protein/KCNJ5_HUMAN"}],"hgncRootFamilies":[{"name":"Ion channels","href":"/api/1.0/gene_family/Ion+channels"}]}