{"symbol":"KCNJ6","synonyms":["KATP-2","KIR3.2","KPLBS","GIRK-2","KATP2","HIGIRK2","BIR1","KCNJ7","GIRK2"],"name":"potassium channel, inwardly rectifying subfamily J, member 6","description":"This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels. This type of potassium channel allows a greater flow of potassium into the cell than out of it. These proteins modulate many physiological processes, including heart rate in cardiac cells and circuit activity in neuronal cells, through G-protein coupled receptor stimulation. Mutations in this gene are associated with Keppen-Lubinsky Syndrome, a rare condition characterized by severe developmental delay, facial dysmorphism, and intellectual disability. [provided by RefSeq, Apr 2015]","ncbiEntrezGeneId":3763,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/3763","proteins":[{"symbol":"KCNJ6_HUMAN","href":"/api/1.0/protein/KCNJ6_HUMAN"}],"hgncRootFamilies":[{"name":"Ion channels","href":"/api/1.0/gene_family/Ion+channels"}]}