{"symbol":"KDM3A","synonyms":["TSGA","JMJD1","JHDM2A","JHMD2A","JMJD1A"],"name":"lysine (K)-specific demethylase 3A","description":"Enables histone H3K9me/H3K9me2 demethylase activity; iron ion binding activity; and nuclear androgen receptor binding activity. Involved in androgen receptor signaling pathway; formaldehyde biosynthetic process; and positive regulation of DNA-templated transcription. Located in nucleoplasm. Implicated in cervical cancer and colon cancer. Biomarker of Ewing sarcoma; hepatocellular carcinoma; nasopharynx carcinoma; and prostate cancer. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":55818,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/55818","proteins":[{"symbol":"KDM3A_HUMAN","href":"/api/1.0/protein/KDM3A_HUMAN"}],"hgncRootFamilies":[{"name":"Chromatin-modifying enzymes","href":"/api/1.0/gene_family/Chromatin-modifying+enzymes"}]}