{"symbol":"KDM4D","synonyms":["JMJD2D"],"name":"lysine (K)-specific demethylase 4D","description":"Enables histone H3K9me2/H3K9me3 demethylase activity. Involved in inflammatory response. Acts upstream of or within several processes, including cellular response to ionizing radiation; double-strand break repair via homologous recombination; and positive regulation of double-strand break repair via nonhomologous end joining. Located in site of double-strand break. Biomarker of nephroblastoma. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":55693,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/55693","proteins":[{"symbol":"KDM4D_HUMAN","href":"/api/1.0/protein/KDM4D_HUMAN"}],"hgncRootFamilies":[{"name":"Chromatin-modifying enzymes","href":"/api/1.0/gene_family/Chromatin-modifying+enzymes"}]}