{"symbol":"KDM5A","synonyms":["RBBP-2","RBBP2","RBP2"],"name":"lysine (K)-specific demethylase 5A","description":"This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts with many other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression. [provided by RefSeq, Aug 2013]","ncbiEntrezGeneId":5927,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5927","proteins":[{"symbol":"KDM5A_HUMAN","href":"/api/1.0/protein/KDM5A_HUMAN"}],"hgncRootFamilies":[{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"},{"name":"Chromatin-modifying enzymes","href":"/api/1.0/gene_family/Chromatin-modifying+enzymes"}]}