{"symbol":"KDM5C","synonyms":["XE169","JARID1C","MRXSJ","MRXSCJ","MRX13","DXS1272E","MRXJ","SMCX"],"name":"lysine (K)-specific demethylase 5C","description":"This gene is a member of the SMCY homolog family and encodes a protein with one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers. The DNA-binding motifs suggest this protein is involved in the regulation of transcription and chromatin remodeling. Mutations in this gene have been associated with X-linked cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]","ncbiEntrezGeneId":8242,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8242","proteins":[{"symbol":"KDM5C_HUMAN","href":"/api/1.0/protein/KDM5C_HUMAN"}],"hgncRootFamilies":[{"name":"X-linked mental retardation","href":"/api/1.0/gene_family/X-linked+mental+retardation"},{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"},{"name":"Chromatin-modifying enzymes","href":"/api/1.0/gene_family/Chromatin-modifying+enzymes"}]}