{"symbol":"KLF1","synonyms":["INLU","HBFQTL6","CDAN4","EKLF","EKLF/KLF1"],"name":"Kruppel-like factor 1 (erythroid)","description":"This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. [provided by RefSeq, Oct 2009]","ncbiEntrezGeneId":10661,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10661","proteins":[{"symbol":"KLF1_HUMAN","href":"/api/1.0/protein/KLF1_HUMAN"}],"hgncRootFamilies":[{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}