{"symbol":"KLF5","synonyms":["IKLF","BTEB2","CKLF"],"name":"Kruppel-like factor 5 (intestinal)","description":"This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. The encoded protein is a transcriptional activator that binds directly to a specific recognition motif in the promoters of target genes. This protein acts downstream of multiple different signaling pathways and is regulated by post-translational modification. It may participate in both promoting and suppressing cell proliferation. Expression of this gene may be changed in a variety of different cancers and in cardiovascular disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]","ncbiEntrezGeneId":688,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/688","proteins":[{"symbol":"KLF5_HUMAN","href":"/api/1.0/protein/KLF5_HUMAN"}],"hgncRootFamilies":[{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}