{"symbol":"KLF8","synonyms":["BKLF3","ZNF741"],"name":"Kruppel-like factor 8","description":"This gene encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]","ncbiEntrezGeneId":11279,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/11279","proteins":[{"symbol":"KLF8_HUMAN","href":"/api/1.0/protein/KLF8_HUMAN"}],"hgncRootFamilies":[{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}