{"symbol":"KLRG1","synonyms":["MAFA-L","MAFA-2F1","MAFA-LIKE","MAFA","CLEC15A"],"name":"killer cell lectin-like receptor subfamily G, member 1","description":"Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Studies in mice suggested that the expression of this gene may be regulated by MHC class I molecules. [provided by RefSeq, Jun 2016]","ncbiEntrezGeneId":10219,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10219","proteins":[{"symbol":"KLRG1_HUMAN","href":"/api/1.0/protein/KLRG1_HUMAN"}],"hgncRootFamilies":[{"name":"Killer cell lectin-like receptors (KLR)","href":"/api/1.0/gene_family/Killer+cell+lectin-like+receptors+%28KLR%29"},{"name":"C-type lectin domain family (CLEC)","href":"/api/1.0/gene_family/C-type+lectin+domain+family+%28CLEC%29"}]}