{"symbol":"KRT19","synonyms":["CK19","K1CS","K19"],"name":"keratin 19, type I","description":"The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":3880,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/3880","proteins":[{"symbol":"K1C19_HUMAN","href":"/api/1.0/protein/K1C19_HUMAN"}],"hgncRootFamilies":[{"name":"Intermediate filaments","href":"/api/1.0/gene_family/Intermediate+filaments"}]}