{"symbol":"KRT20","synonyms":["KRT21","CK20","K20","CK-20"],"name":"keratin 20, type I","description":"The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":54474,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/54474","proteins":[{"symbol":"K1C20_HUMAN","href":"/api/1.0/protein/K1C20_HUMAN"}],"hgncRootFamilies":[{"name":"Intermediate filaments","href":"/api/1.0/gene_family/Intermediate+filaments"}]}