{"symbol":"KRT83","synonyms":["HB-3","KRTHB3","EKVP5","HB3","MNLIX"],"name":"keratin 83, type II","description":"The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB1 and KRTHB6, is found primarily in the hair cortex. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":3889,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/3889","proteins":[{"symbol":"KRT83_HUMAN","href":"/api/1.0/protein/KRT83_HUMAN"}],"hgncRootFamilies":[{"name":"Intermediate filaments","href":"/api/1.0/gene_family/Intermediate+filaments"}]}