{"symbol":"LAMA1","synonyms":["PTBHS","S-LAM-ALPHA","LAMA"],"name":"laminin, alpha 1","description":"This gene encodes one of the alpha 1 subunits of laminin. The laminins are a family of extracellular matrix glycoproteins that have a heterotrimeric structure consisting of an alpha, beta and gamma chain. These proteins make up a major component of the basement membrane and have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Mutations in this gene may be associated with Poretti-Boltshauser syndrome. [provided by RefSeq, Sep 2014]","ncbiEntrezGeneId":284217,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/284217","proteins":[{"symbol":"LAMA1_HUMAN","href":"/api/1.0/protein/LAMA1_HUMAN"}],"hgncRootFamilies":[{"name":"Laminins (LAM)","href":"/api/1.0/gene_family/Laminins+%28LAM%29"}]}