{"symbol":"LAMTOR1","synonyms":["P27RF-RHO","PDRO","RAGULATOR1","C11ORF59"],"name":"late endosomal/lysosomal adaptor, MAPK and MTOR activator 1","description":"Enables GTPase binding activity and protein-membrane adaptor activity. Contributes to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Involved in several processes, including cholesterol homeostasis; positive regulation of TORC1 signaling; and regulation of cholesterol transport. Located in lysosome. Part of FNIP-folliculin RagC/D GAP. Is active in Ragulator complex and lysosomal membrane. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":55004,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/55004","proteins":[{"symbol":"LTOR1_HUMAN","href":"/api/1.0/protein/LTOR1_HUMAN"}],"hgncRootFamilies":[]}