{"symbol":"LAMTOR3","synonyms":["MAP2K1IP1","RAGULATOR3","MAPBP","PRO0633","MAPKSP1"],"name":"late endosomal/lysosomal adaptor, MAPK and MTOR activator 3","description":"This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13. [provided by RefSeq, Aug 2011]","ncbiEntrezGeneId":8649,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8649","proteins":[{"symbol":"LTOR3_HUMAN","href":"/api/1.0/protein/LTOR3_HUMAN"}],"hgncRootFamilies":[]}