{"symbol":"LCP2","synonyms":["SLP-76","SLP76"],"name":"lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)","description":"This gene encodes an adapter protein that acts as a substrate of the T cell antigen receptor (TCR)-activated protein tyrosine kinase pathway. The encoded protein associates with growth factor receptor bound protein 2, and is thought to play a role TCR-mediated intracellular signal transduction. A similar protein in mouse plays a role in normal T-cell development and activation. Mice lacking this gene show subcutaneous and intraperitoneal fetal hemorrhaging, dysfunctional platelets and impaired viability. [provided by RefSeq, Nov 2016]","ncbiEntrezGeneId":3937,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/3937","proteins":[{"symbol":"LCP2_HUMAN","href":"/api/1.0/protein/LCP2_HUMAN"}],"hgncRootFamilies":[{"name":"SH2 domain containing","href":"/api/1.0/gene_family/SH2+domain+containing"}]}