{"symbol":"LILRA3","synonyms":["CD85E","HM31","HM43","ILT6","ILT-6","LIR-4","LIR4"],"name":"leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3","description":"This gene encodes a member of a family of immunoreceptors that are expressed predominantly in monocytes and B cells, and at lower levels in dendritic cells and natural killer cells. The encoded protein lacks the transmembrane region found in other members of this family. It acts as a soluble receptor for class I major histocompatibility complex (MHC) antigens. Alternatively spliced transcript variants encoding different isoforms have been found. This gene is located in a cluster of related genes on chromosome 19 and is polymorphic in human populations, with many individuals containing a deletion of this genomic region. [provided by RefSeq, Mar 2014]","ncbiEntrezGeneId":11026,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/11026","proteins":[{"symbol":"LIRA3_HUMAN","href":"/api/1.0/protein/LIRA3_HUMAN"}],"hgncRootFamilies":[{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"},{"name":"Immunoglobulin superfamily domain containing","href":"/api/1.0/gene_family/Immunoglobulin+superfamily+domain+containing"}]}