{"symbol":"LINC-ROR","synonyms":["lincRNA-ST8SIA3","LINCRNA-ROR","ROR"],"name":"long intergenic non-protein coding RNA, regulator of reprogramming","description":"This gene produces a long non-coding RNA that regulates the reprogramming of pluripotent stem cells. This RNA suppresses induction of tumor protein p53 after DNA damage. It is thought to act as a sponge for microRNAs that regulate stem cell factors POU class 5 homeobox 1, Nanog, and SRY-box 2. This RNA may also have a extracellular role in modulating response to hypoxia in hepatocellular cancer cells. Expression of this transcript is associated with tumor progression and epithelial to mesenchymal transition and metastasis. [provided by RefSeq, Dec 2017]","ncbiEntrezGeneId":100885779,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/100885779","proteins":[],"hgncRootFamilies":[{"name":"Non-coding RNAs","href":"/api/1.0/gene_family/Non-coding+RNAs"}]}