{"symbol":"LINGO1","synonyms":["UNQ201","MRT64","LERN1","LRRN6A"],"name":"leucine rich repeat and Ig domain containing 1","description":"Predicted to enable epidermal growth factor receptor binding activity. Predicted to act upstream of or within negative regulation of oligodendrocyte differentiation; negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; and neuron development. Predicted to be located in plasma membrane. Predicted to be active in several cellular components, including extracellular space; glutamatergic synapse; and presynapse. Implicated in autosomal recessive intellectual developmental disorder 64 and glaucoma. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":84894,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/84894","proteins":[{"symbol":"LIGO1_HUMAN","href":"/api/1.0/protein/LIGO1_HUMAN"}],"hgncRootFamilies":[{"name":"Immunoglobulin superfamily domain containing","href":"/api/1.0/gene_family/Immunoglobulin+superfamily+domain+containing"}]}