{"symbol":"LIPC","synonyms":["LIPH","HTGL","HDLCQ12"],"name":"lipase, hepatic","description":"Enables phospholipase A1 activity and triacylglycerol lipase activity. Involved in several processes, including cholesterol homeostasis; plasma lipoprotein particle remodeling; and triglyceride catabolic process. Located in extracellular space. Implicated in several diseases, including Alzheimer\u0027s disease; coronary artery disease; familial combined hyperlipidemia; peripheral vascular disease; and type 2 diabetes mellitus. Biomarker of hyperinsulinism; obesity; and type 1 diabetes mellitus. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":3990,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/3990","proteins":[{"symbol":"LIPC_HUMAN","href":"/api/1.0/protein/LIPC_HUMAN"}],"hgncRootFamilies":[{"name":"Lipases","href":"/api/1.0/gene_family/Lipases"}]}