{"symbol":"LMO1","synonyms":["RBTN1","RHOM1","TTG1"],"name":"LIM domain only 1 (rhombotin 1)","description":"This locus encodes a transcriptional regulator that contains two cysteine-rich LIM domains but lacks a DNA-binding domain. LIM domains may play a role in protein interactions; thus the encoded protein may regulate transcription by competitively binding to specific DNA-binding transcription factors. Alterations at this locus have been associated with acute lymphoblastic T-cell leukemia. Chromosomal rearrangements have been observed between this locus and at least two loci, the delta subunit of the T-cell antigen receptor gene and the LIM domain binding 1 gene. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2012]","ncbiEntrezGeneId":4004,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4004","proteins":[{"symbol":"RBTN1_HUMAN","href":"/api/1.0/protein/RBTN1_HUMAN"}],"hgncRootFamilies":[]}