{"symbol":"LPL","synonyms":["LIPD","HDLCQ11"],"name":"lipoprotein lipase","description":"LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":4023,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4023","proteins":[{"symbol":"LIPL_HUMAN","href":"/api/1.0/protein/LIPL_HUMAN"}],"hgncRootFamilies":[{"name":"Lipases","href":"/api/1.0/gene_family/Lipases"}]}