{"symbol":"LPP","synonyms":[],"name":"LIM domain containing preferred translocation partner in lipoma","description":"This gene encodes a member of a subfamily of LIM domain proteins that are characterized by an N-terminal proline-rich region and three C-terminal LIM domains. The encoded protein localizes to the cell periphery in focal adhesions and may be involved in cell-cell adhesion and cell motility. This protein also shuttles through the nucleus and may function as a transcriptional co-activator. This gene is located at the junction of certain disease-related chromosomal translocations, which result in the expression of chimeric proteins that may promote tumor growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]","ncbiEntrezGeneId":4026,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4026","proteins":[{"symbol":"LPP_HUMAN","href":"/api/1.0/protein/LPP_HUMAN"}],"hgncRootFamilies":[]}