{"symbol":"LRPPRC","synonyms":["LRP130","LSFC","CLONE-23970"],"name":"leucine-rich pentatricopeptide repeat containing","description":"This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome. [provided by RefSeq, Mar 2012]","ncbiEntrezGeneId":10128,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10128","proteins":[{"symbol":"LPPRC_HUMAN","href":"/api/1.0/protein/LPPRC_HUMAN"}],"hgncRootFamilies":[]}