{"symbol":"LRSAM1","synonyms":["CMT2P","RIFLE"],"name":"leucine rich repeat and sterile alpha motif containing 1","description":"This gene encodes a ring finger protein involved in a variety of functions, including regulation of signaling pathways and cell adhesion, mediation of self-ubiquitylation, and involvement in cargo sorting during receptor endocytosis. Mutations in this gene have been associated with Charcot-Marie-Tooth disease. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jan 2012]","ncbiEntrezGeneId":90678,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/90678","proteins":[{"symbol":"LRSM1_HUMAN","href":"/api/1.0/protein/LRSM1_HUMAN"}],"hgncRootFamilies":[{"name":"Sterile alpha motif (SAM) domain containing (SAMD)","href":"/api/1.0/gene_family/Sterile+alpha+motif+%28SAM%29+domain+containing+%28SAMD%29"}]}