{"symbol":"LYST","synonyms":["CHS1","CHS"],"name":"lysosomal trafficking regulator","description":"This gene encodes a protein that regulates intracellular protein trafficking in endosomes, and may be involved in pigmentation. Mutations in this gene are associated with Chediak-Higashi syndrome, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants, though the full-length nature of some of these variants has not been determined. [provided by RefSeq, Apr 2013]","ncbiEntrezGeneId":1130,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/1130","proteins":[{"symbol":"LYST_HUMAN","href":"/api/1.0/protein/LYST_HUMAN"}],"hgncRootFamilies":[{"name":"WD repeat domain containing (WDR)","href":"/api/1.0/gene_family/WD+repeat+domain+containing+%28WDR%29"}]}