{"symbol":"MACF1","synonyms":["OFC4","MACF","ACF7","ABP620"],"name":"microtubule-actin crosslinking factor 1","description":"This gene encodes a large protein containing numerous spectrin and leucine-rich repeat (LRR) domains. The encoded protein is a member of a family of proteins that form bridges between different cytoskeletal elements. This protein facilitates actin-microtubule interactions at the cell periphery and couples the microtubule network to cellular junctions. Alternative splicing results in multiple transcript variants, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, May 2013]","ncbiEntrezGeneId":23499,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/23499","proteins":[{"symbol":"MACF1_HUMAN","href":"/api/1.0/protein/MACF1_HUMAN"}],"hgncRootFamilies":[{"name":"EF-hand domain containing","href":"/api/1.0/gene_family/EF-hand+domain+containing"},{"name":"Plakins","href":"/api/1.0/gene_family/Plakins"}]}