{"symbol":"MAML1","synonyms":["MAM1","MAM-1"],"name":"mastermind-like 1 (Drosophila)","description":"This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":9794,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/9794","proteins":[{"symbol":"MAML1_HUMAN","href":"/api/1.0/protein/MAML1_HUMAN"}],"hgncRootFamilies":[]}