{"symbol":"MAN2A1","synonyms":["MANA2","AMAN II","GOLIM7","MANII"],"name":"mannosidase, alpha, class 2A, member 1","description":"This gene encodes a glycosyl hydrolase that localizes to the Golgi and catalyzes the final hydrolytic step in the asparagine-linked oligosaccharide (N-glycan) maturation pathway. Mutations in the mouse homolog of this gene have been shown to cause a systemic autoimmune disease similar to human systemic lupus erythematosus. [provided by RefSeq, Dec 2013]","ncbiEntrezGeneId":4124,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4124","proteins":[{"symbol":"MA2A1_HUMAN","href":"/api/1.0/protein/MA2A1_HUMAN"}],"hgncRootFamilies":[]}