{"symbol":"MAP3K14","synonyms":["HSNIK","NIK","HS","FTDCR1B"],"name":"mitogen-activated protein kinase kinase kinase 14","description":"This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":9020,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/9020","proteins":[{"symbol":"M3K14_HUMAN","href":"/api/1.0/protein/M3K14_HUMAN"}],"hgncRootFamilies":[{"name":"Mitogen-activated protein kinase cascade","href":"/api/1.0/gene_family/Mitogen-activated+protein+kinase+cascade"}]}