{"symbol":"MARCO","synonyms":["SR-A6","SCARA2"],"name":"macrophage receptor with collagenous structure","description":"The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":8685,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8685","proteins":[{"symbol":"MARCO_HUMAN","href":"/api/1.0/protein/MARCO_HUMAN"}],"hgncRootFamilies":[]}