{"symbol":"MAS1","synonyms":["MAS","MGRA"],"name":"MAS1 proto-oncogene, G protein-coupled receptor","description":"This gene encodes a class I seven-transmembrane G-protein-coupled receptor. The encoded protein is a receptor for angiotensin-(1-7) and preferentially couples to the Gq protein, activating the phospholipase C signaling pathway. The encoded protein may play a role in multiple processes including hypotension, smooth muscle relaxation and cardioprotection by mediating the effects of angiotensin-(1-7). [provided by RefSeq, May 2012]","ncbiEntrezGeneId":4142,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4142","proteins":[{"symbol":"MAS_HUMAN","href":"/api/1.0/protein/MAS_HUMAN"}],"hgncRootFamilies":[{"name":"G protein-coupled receptors","href":"/api/1.0/gene_family/G+protein-coupled+receptors"}]}