{"symbol":"MAST1","synonyms":["SAST","SAST170"],"name":"microtubule associated serine/threonine kinase 1","description":"This gene is a member of the microtubule-associated serine/threonine kinase (MAST) family. The protein encoded by this gene has an N-terminal serine/threonine kinase domain followed by a postsynaptic density protein-95/discs large/zona occludens-1 (PDZ) domain. In mouse and rat, the orthologous protein associates with the cytoskeleton and can bind both beta-2-syntrophin and neuronal nitric oxide synthase (nNOS) through its PDZ domain. In mouse and rat, this protein also co-localizes with dystrophin- and utrophin-associated protein complexes (DAPC/UAPC) in the vascular endothelium of the central nervous system. [provided by RefSeq, May 2017]","ncbiEntrezGeneId":22983,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/22983","proteins":[{"symbol":"MAST1_HUMAN","href":"/api/1.0/protein/MAST1_HUMAN"}],"hgncRootFamilies":[]}