{"symbol":"MB21D1","synonyms":["CGAS","H-CGAS","C6ORF150"],"name":"Mab-21 domain containing 1","description":"Enables several functions, including 2\u0027,3\u0027-cyclic GMP-AMP synthase activity; molecular condensate scaffold activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in several processes, including defense response to symbiont; intracellular signal transduction; and regulation of defense response. Located in nuclear body; plasma membrane; and site of double-strand break. Is active in cytosol and nucleus. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":115004,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/115004","proteins":[{"symbol":"CGAS_HUMAN","href":"/api/1.0/protein/CGAS_HUMAN"}],"hgncRootFamilies":[]}