{"symbol":"MCC","synonyms":["MCC1"],"name":"mutated in colorectal cancers","description":"This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":4163,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4163","proteins":[{"symbol":"CRCM_HUMAN","href":"/api/1.0/protein/CRCM_HUMAN"}],"hgncRootFamilies":[{"name":"EF-hand domain containing","href":"/api/1.0/gene_family/EF-hand+domain+containing"}]}