{"symbol":"MCCC1","synonyms":["MCC-B","MCCA"],"name":"methylcrotonoyl-CoA carboxylase 1 (alpha)","description":"This gene encodes the large subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":56922,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/56922","proteins":[{"symbol":"MCCA_HUMAN","href":"/api/1.0/protein/MCCA_HUMAN"}],"hgncRootFamilies":[]}