{"symbol":"MCCC2","synonyms":["MCCB"],"name":"methylcrotonoyl-CoA carboxylase 2 (beta)","description":"This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2018]","ncbiEntrezGeneId":64087,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/64087","proteins":[{"symbol":"MCCB_HUMAN","href":"/api/1.0/protein/MCCB_HUMAN"}],"hgncRootFamilies":[]}