{"symbol":"MCPH1","synonyms":["BRIT1"],"name":"microcephalin 1","description":"This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010]","ncbiEntrezGeneId":79648,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/79648","proteins":[{"symbol":"MCPH1_HUMAN","href":"/api/1.0/protein/MCPH1_HUMAN"}],"hgncRootFamilies":[]}