{"symbol":"MDFIC","synonyms":["HIC","MDFIC1"],"name":"MyoD family inhibitor domain containing","description":"This gene product is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization; p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]","ncbiEntrezGeneId":29969,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/29969","proteins":[{"symbol":"MDFIC_HUMAN","href":"/api/1.0/protein/MDFIC_HUMAN"}],"hgncRootFamilies":[]}