{"symbol":"MDH2","synonyms":["M-MDH","MDH","EIEE51","MOR1","MGC:3559"],"name":"malate dehydrogenase 2, NAD (mitochondrial)","description":"Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]","ncbiEntrezGeneId":4191,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4191","proteins":[{"symbol":"MDHM_HUMAN","href":"/api/1.0/protein/MDHM_HUMAN"}],"hgncRootFamilies":[]}