{"symbol":"MGAT1","synonyms":["GNT-1","GLCNAC-TI","GLYT1","MGAT","GnTI","GLCT1","GNT-I"],"name":"mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase","description":"There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis. Several variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":4245,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4245","proteins":[{"symbol":"MGAT1_HUMAN","href":"/api/1.0/protein/MGAT1_HUMAN"}],"hgncRootFamilies":[{"name":"Glycosyltransferases","href":"/api/1.0/gene_family/Glycosyltransferases"}]}