{"symbol":"MGME1","synonyms":["MTDPS11","DDK1","C20ORF72","BA504H3.4"],"name":"mitochondrial genome maintenance exonuclease 1","description":"The protein encoded by this gene is a nuclear-encoded mitochondrial protein necessary for the maintenance of mitochondrial genome synthesis. The encoded protein is a RecB-type exonuclease and primarily cleaves single-stranded DNA. Defects in this gene have been associated with mitochondrial DNA depletion syndrome-11. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015]","ncbiEntrezGeneId":92667,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/92667","proteins":[{"symbol":"MGME1_HUMAN","href":"/api/1.0/protein/MGME1_HUMAN"}],"hgncRootFamilies":[{"name":"Exonucleases","href":"/api/1.0/gene_family/Exonucleases"}]}