{"symbol":"MITD1","synonyms":[],"name":"MIT, microtubule interacting and transport, domain containing 1","description":"Abscission, the separation of daughter cells at the end of cytokinesis, is effected by endosomal sorting complexes required for transport III (ESCRT-III). The protein encoded by this gene functions as a homodimer, with the N-termini binding to a subset of ESCRT-III subunits and the C-termini binding to membranes. The encoded protein regulates ESCRT-III activity and is required for proper cytokinesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]","ncbiEntrezGeneId":129531,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/129531","proteins":[{"symbol":"MITD1_HUMAN","href":"/api/1.0/protein/MITD1_HUMAN"}],"hgncRootFamilies":[]}