{"symbol":"MPHOSPH8","synonyms":["TWA3","MPP8","HSMPP8"],"name":"M-phase phosphoprotein 8","description":"Enables chromatin binding activity; histone reader activity; and methylated histone binding activity. Involved in negative regulation of gene expression via chromosomal CpG island methylation and transposable element silencing by heterochromatin formation. Located in several cellular components, including cytosol; heterochromatin; and nuclear lumen. Part of nucleosome. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":54737,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/54737","proteins":[{"symbol":"MPP8_HUMAN","href":"/api/1.0/protein/MPP8_HUMAN"}],"hgncRootFamilies":[{"name":"Ankyrin repeat domain containing (ANKRD)","href":"/api/1.0/gene_family/Ankyrin+repeat+domain+containing+%28ANKRD%29"}]}