{"symbol":"MPI","synonyms":["PMI1","CDG1B","PMI"],"name":"mannose phosphate isomerase","description":"Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]","ncbiEntrezGeneId":4351,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4351","proteins":[{"symbol":"MPI_HUMAN","href":"/api/1.0/protein/MPI_HUMAN"}],"hgncRootFamilies":[]}