{"symbol":"MPO","synonyms":[],"name":"myeloperoxidase","description":"Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014]","ncbiEntrezGeneId":4353,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/4353","proteins":[{"symbol":"PERM_HUMAN","href":"/api/1.0/protein/PERM_HUMAN"}],"hgncRootFamilies":[]}