{"symbol":"MPP5","synonyms":["PALS1"],"name":"membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)","description":"This gene encodes a member of the p55-like subfamily of the membrane-associated guanylate kinase (MAGUK) gene superfamily. The encoded protein participates in the polarization of differentiating cells, has been shown to regulate myelinating Schwann cells (PMID: 20237282), and is one of the components of the Crumbs complex in the retina. Mice which express lower levels of the orthologous protein have retinal degeneration and impaired vision (PMID: 22114289). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]","ncbiEntrezGeneId":64398,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/64398","proteins":[{"symbol":"MPP5_HUMAN","href":"/api/1.0/protein/MPP5_HUMAN"}],"hgncRootFamilies":[{"name":"Membrane-associated guanylate kinases","href":"/api/1.0/gene_family/Membrane-associated+guanylate+kinases"}]}