{"symbol":"MRC2","synonyms":["CD280","CLEC13E","ENDO180","UPARAP"],"name":"mannose receptor, C type 2","description":"This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease. [provided by RefSeq, Feb 2012]","ncbiEntrezGeneId":9902,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/9902","proteins":[{"symbol":"MRC2_HUMAN","href":"/api/1.0/protein/MRC2_HUMAN"}],"hgncRootFamilies":[{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"},{"name":"C-type lectin domain family (CLEC)","href":"/api/1.0/gene_family/C-type+lectin+domain+family+%28CLEC%29"}]}