{"symbol":"MRPL10","synonyms":["MRPL8","RPML8","MRP-L10","MRP-L8","L10MT"],"name":"mitochondrial ribosomal protein L10","description":"Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode two different isoforms. A pseudogene corresponding to this gene is found on chromosome 5q. [provided by RefSeq, Nov 2010]","ncbiEntrezGeneId":124995,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/124995","proteins":[{"symbol":"RM10_HUMAN","href":"/api/1.0/protein/RM10_HUMAN"}],"hgncRootFamilies":[{"name":"Mitochondrial ribosomal proteins (MRPL, MRPS)","href":"/api/1.0/gene_family/Mitochondrial+ribosomal+proteins+%28MRPL%2C+MRPS%29"}]}